Reversing Chronic Kidney Disease with Niacin and Sodium Bicarbonate: Review and Commentary

Plain-Language Summary

This review and commentary, co-authored by Stephen McConnell, looks at cases where people with early-stage chronic kidney disease saw their disease stage improve after adding low-dose niacin and sodium bicarbonate. It walks through the biochemistry behind why the authors believe this combination may help, including its effect on phosphate levels, and includes a personal account from Stephen about his own father's kidney disease.

Key Concepts

• Co-authored by Stephen McConnell and W. Todd Penberthy, published by the Orthomolecular Medicine News Service.
• Reviews documented cases of chronic kidney disease stage improvement associated with low-dose niacin and sodium bicarbonate.
• Discusses proposed mechanisms, including NAD synthesis, PCSK9 inhibition, sodium transporter effects, and PPAR gamma activation.
• Includes a personal account from Stephen McConnell about his father's experience with chronic kidney disease.

Stephen's Role

Lead Author

Citation

McConnell, S., & Penberthy, W. T. (2021, October 14). Reversing chronic kidney disease with niacin and sodium bicarbonate: Review and commentary. Orthomolecular Medicine News Service.

External Source

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